Standard Available Services
Whole Genome Sequencing
To identify genomic variants (SNP/indels) comparatively. Usually involves comparing to a reference, also for cross sample comparisons.
Small Genome De Novo Assembly
For small genomes (bacteria, small eukaryotes), we can build a new assembly. This process is generally more straightforward for small organisms.
Large Genome De Novo Assembly
For larger genomes (human, mouse, most plants), this process is generally more iterative to build a new assembly.
To identify genes that are differentially expressed between conditions, and potentially identify perturbed biological pathways.
Single Cell RNA Analysis
RNA-seq analysis at single cell clarity. This generally involves the 10X Genomics workflow for library preparations.
scRNA with additional flavors
Additional 10X Genomics scRNA-seq modalities such as feature barcoding, hashtagging, and VDJ sequencing.
To identify the open chromatin (unbound from nucleosomes) regions between conditions
ATAC-seq at single cell clarity using 10X Genomics library preparations.
10X Genomics scATAC with additional modalities, such as multiome.
To identify differentially methylated regions between conditions.
To identify differential transcription factor binding between conditions.
To identify differential binding sites of DNA-associated proteins between conditions.
Amplicon based metabarcoding to identify present bacterial populations.
Short Read Shotgun Metagenomics
Whole genome metagenomics using short reads technologies (Illumina)
Long Read Shotgun Metagenomics
Whole genome metagenomics using long reads technology (Nanopore)
Where magic requests happen
Projects that can be customized to multiple applications, such as Ampli-seq, VDJ sequencing, tool development etc.